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Polyclonal Antibody to 3-Hydroxy-3-Methylglutaryl Coenzyme

The antigen used was a peptide containing the phosphosite of interest. The plot shows the absorbance against the antibody dilution for phosphopeptide antigen and non-phosphorylated peptide antigen. HMGCR antibody LS-C318764 is an HRP-conjugated rabbit polyclonal antibody to human HMGCR (HMG-CoA Reductase). Validated for ELISA, IHC and WB. HMGCR Antibody detects endogenous levels of total HMGCR. RRID: AB_2838480 Please cite this product as: Affinity Biosciences Cat# DF6518, RRID:AB_2838480. Format: Liquid.

Hmgcr antibody

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(Showing 1 - 1 of 1 FAQs). If we use this antibody for western blot, what is the predicted protein size? HMGCR is a 887 amino acids long protein with a predicted size of 96.7 kDa. Anti-HMGCR antibody produced in rabbit Prestige Antibodies ® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution Synonym: Anti-3-Hydroxy-3-methylglutaryl-CoA reductase Human Protein Atlas Number HPA008338 Human Protein Atlas - View RNA & protein expression data of this target 2016-10-01 · Anti-HMGCR antibodies showed good discrimination between (a) immune-mediated necrotizing myopathies (IMNM) and all controls (except idiopathic inflammatory myopathies (IIM)), (b) IMNM and all controls, (c) IMNM vs. IIM. (d) Moderate discrimination was also found for all IIM (including IMNM) vs. all controls. Select HMGCR antibodies from monoclonal antibodies listed below.

Targeting HMG-CoA reductase with statins in a window-of

Immunogen … IgG antibodies to HMGCR in the setting of muscle weakness and a raised CK are highly suggestive of an autoimmune necrotising myositis. Many cases are associated with statin exposure although this is not universal.

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Hmgcr antibody

Anti-HMGCR myopathy was first recognized and characterized in patients with a history of statin exposure and immune-mediated necrotizing myopathy. After the discovery of anti-HMGCR autoantibodies, several international groups identified and characterized more patients, expanding the phenotypic spect …. HMGCR : Evaluating patients with suspected necrotizing autoimmune myopathy Measuring 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibodies HMGCR - Overview: 3-Hydroxy-3-Methylglutaryl Coenzyme-A (HMG-CoA) Reductase, Serum Antibodies against HMG-CoA reductase (HMGCR) are associated with necrotizing autoimmune-myopathy and can be detected in about 25% of these patients. Antibodies against HMGCR are associated with elevated levels of creatine kinase (CK) in blood.

Hmgcr antibody

Vincent Tiffreau1,3. May 11, 2016 Recently, it has been recognised that in rare instances, statins can induce an immune‐mediated necrotising myositis with antibodies against 3‐  Custom recombinant monoclonal antibody generation by Bio-Rad using HuCAL ® technology could allow you to carry out research that was previously  Sep 29, 2017 LGI1/CASPR2-antibody encephalitis is an autoimmune encephalitis in which antibodies target LGI1 (leucine-rich glioma inactivated 1) or  The ImmPRESS Excel kits are a two-step peroxidase polymer based detection system that include an unconjugated amplifier antibody.
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Hmgcr antibody

HMGCR antibody myositis presenting as limb girdle muscular dystrophy (oktober 2020) LIA f, u f, u SRP-antikroppar HMGCR-antikroppar SRPAb HMGCRAb Kä Anti-phospholipid antibodies may indicate phospholipid antibody syndrome.

Boster Bio Anti-HMGCR Antibody catalog # A00643-2. Tested in IP, WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 100ul in Liquid form antibody. HMGCR has a mass of 97.48kDa and an amino acid length of 888.
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HMGCR Antibody H-300 SCBT - Santa Cruz Biotechnology

av A Miettinen — HMGCR-antikroppar cellular antigens referred to as anti-nuclear antibodies. ANA, ENA, dsDNA antibodies with newer tests help in the diagnostics of ARDs,. Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer Exploring epitopes of antibodies toward the human tryptophanyl-tRNA  Anti-VGPC, Anti-VGKCs, Voltage-gated potassium channels antibody, LGI-1, CASPR2 · Klinisk immunologi och HMGCR ak · Klinisk immunologi och  antigen identified by monoclonal antibody Ki 67, protein_coding, 3.51E-06, FALSE 662, 15357, Hmgcr, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase  av H Tryggvadottir — Moderate/strong HMGCR levels were associated with older age and favorable tumor characteristics but not with breast cancer-free interval. IMNM har stark association med SRP och HMGCR-antikroppar.